All functions

CheckOvercompression()

Check if DMR calling seed number is ovcompressed.

DefineBestPC()

Identify your best principle component.

Get_Novel_DMRs()

Call DMRs from WGBS data.

MethyDiff_Set()

Add a mean methylation column to a data.frame of regions.

MethylDiff()

Get the mean methylation difference across a specified region.

Ol_Reliable()

PCBS ggplot theme.

addRanks()

Add ranks to eigenvector scores.

checkRank()

Check rank cut-off values manually.

chromDict()

Convert a rank object into a chromDict.

chromDictMeth()

Create a chromDict of percent methylation difference at all sites.

eigen

Simulated WGBS data for PCBS vignettes

getPCRanks()

Get CpG eigenvector scores from a principle component.

getRegionScores()

Calculated methylation significance in a set of regions.

get_all_DMRs()

Nested DMR calling function within Get_Novel_DMRs()

lin()

Find y value of linear regression given x.

lmIntx()

PC-Intersect nested function.

methylDiff_metagene()

Make a metagene from mean percent methylation differences.

multiple_metagenes()

Plot multiple metagene data objects on a single plot.

oneSeed()

Nested DMR calling function within within get_all_DMRs(), Get_Novel_DMRs()

plot_metagene()

Generate a metagene plot from raw metagene data.

rankDist()

Identify the best rank cut-off for significant CpGs.

score_metagene()

Make a metagene from PC Scores.

se()

Standard error of a vector.

tilt()

Component of PCBS ggplot theme.

trimDMR()

Nested DMR calling function within within Get_Novel_DMRs()